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German Clinical Trials Register; 25/10/2021; TrialID: DRKS00026955
Clinical Trial Register | ICTRP | ID: ictrp-DRKS00026955

ABSTRACT

Condition:

COVID19
F41.2;Mixed anxiety and depressive disorder;F41.2

Intervention:

Group 1: Psychobiotic (Lactobacillus helveticus Rosell-52 i Bifidobacterium longum Rosell-175 in dose 3x10 9 CFU) for 6 weeks, 1 capsule per day
Group 2: Placebo for 6 weeks, 1 capsule per day

Primary outcome:

feeling anxiety and depression (HSCL-90, Hopkins Symptom Checklist)

Criteria:

Inclusion criteria: - Patient-reported postovid depression or anxiety changes (score = 12 on the HADS-anxiety subscale (HADS-A) and / or on the HADS-depression subscale (HADS-D),
- consent to participate in the study


Exclusion criteria: - pregnancy,
- severe coexisting diseases (liver cirrhosis, portal hypertension, renal failure, neoplastic diseases, diabetes, connective tissue diseases) and menopause,
- previously (pre-covid) diagnosed mental illnesses, psychiatric treatment,
- taking psychotropic drugs, stimulating / activating dietary supplements (ginger, guarana, ginseng, melatonin), drugs

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